Felice A. Tager, Ph.D., Brian A. Fallon, M.D., John Keilp, Ph.D., Marian Rissenberg, Ph.D., Charles Ray Jones, M.D., and Michael R. Liebowitz, M.D.
https://neuro.psychiatryonline.org/doi/ ... p.13.4.500
In contrast, our study demonstrates that children whose diagnosis and treatment are delayed may suffer considerable impairment. The present study, comparable to Belman et al.22 and Bloom et al.,12 indicates that children with chronic neurologic LYD can have significant neuropsychiatric problems.
Our study raises the question of whether a repeated course of antibiotics would be helpful. Only a placebo-controlled treatment study can answer this question and determine whether neuropsychiatric problems are due to past damage or secondary to persistent infection.
Our findings have relevance to mental health professionals as well as educators working in Lyme-endemic areas, who may be the first to recognize the possible underlying infectious origin of the neuropsychiatric disorder. Recognizing that LYD may present with neuropsychiatric symptoms can lead to timely diagnosis and treatment. Furthermore, identification of children with persistent neuroborreliosis is imperative so that these children can receive the most appropriate medical, psychological, and educational assistance.