Vervolg op; Bron
viewtopic.php?f=5&t=2595&start=490#p30551 en vervolg op; Bron
viewtopic.php?f=5&t=2595&start=490#p30552MDPI
Publicatie 25 juli 2024Open Access Article:
'Biomarker-Based Analysis of Pain in Patients with Tick-Borne Infections before and after Antibiotic Treatment' by
Kunal Garg
1,†, Abbie Thoma 2,†, Gordana Avramovic 2, Leona Gilbert
1, Marc Shawky 3, Minha Rajput Ray 4 and John Shearer Lambert
2,5,6,
*; Bron
https://www.mdpi.com/2079-6382/13/8/693 1 Te?ted Oy, 40100 Jyväskylä, Finland
2 Department of Infectious Diseases, Catherine Mc Auley Education & Research Centre, Mater Misericordiae University Hospital, 21 Nelson Street, Dublin 7, D07 A8NN Dublin, Ireland
3 Université de Technologie de Compiègne, Costech Laboratory, Alliance Sorbonne Université, Centre de Recherches, 60203 Compiègne, France
4 Curaidh Clinic: Innovative Solutions for Pain, Chronic Disease and Work Health, Perth PH2 8EH, UK
5 Catherine Mc Auley Education & Research Centre, University College Dublin, 21 Nelson Street, Dublin 7, D07 A8NN Dublin, Ireland
6 Infectious Diseases Department, The Rotunda Hospital, D01 P5W9 Dublin, Ireland
* Author to whom correspondence should be addressed.
† These authors contributed equally to this work..
..Conflicts of Interest
K.G. and L.G. have a financial and economic stake in ‘Te?ted Oy’, but they do not have any commercial collaborations with the writers of this paper..
..Institutional Review Board Statement
This study received ethics approval from the Institutional Review Board of the Mater Misericordiae University Hospital (Institutional Review Board Reference: 1/378/1946). It complies with the study protocol (version 6), the EU CT Directive 2001/20/EC, GCP Commission Directive 2005/28/EC, ICH/GCP, the Declaration of Helsinki (1996 Version), and all other local and international applicable regulatory requirements..
..4.2. Patient Cohort and Sample Size Estimation
This study invited individuals over 16 who obtained consultations at the outpatient infectious diseases clinic at The Mater Misericordiae University Hospital in Ireland..
Is het gestelde juist? De studie met bevindingen is
géén onafhankelijk onderzoek! En er zijn commerciële samenwerkingsverbanden tussen de
auteurs! En Lambert is consultant bij
Mater Misericordiae University Hospital; Bron
https://www.mater.ie/consultants/ en Bron
https://www.mater.ie/services/infectiou ... /index.xmlGilbert van Tezted (Finland) (
fabrikant!) en Lambert van Lyme Resource Centre (LRC) Dublin (Ierland) en de
Reviewer 1; Bron
https://www.mdpi.com/2079-6382/13/8/693/review_report werken samen in de
'Advisory Panel' van AONM; Bron
https://aonm.org/about/Er wordt reeds
jarenlang samengewerkt! Lyme Resource Centre (LRC) conferentie
14 september 2019 Dublin - 'Tick-borne Disease Diagnostics: The Good the Bad and the Ugly - Dr. Leona Gilbert'; Bron
https://www.youtube.com/watch?v=YNqk3HNHUTc In een kritisch artikel van de wetenschapsjournalist Schneider van
14 februari 2023 - Chronic Lymerics (Tezted Finland); Bron
https://forbetterscience.com/2023/02/14 ... xcellence/ is opmerkelijke informatie genoemd dat goed is te
verifiëren.
..
MDPI has announced a special issue where you already know what horrors to expect. The journal Microorganisms has an open call for papers for a Special Issue titled “Emerging Research on Tick-Borne Pathogens and Diseases” edited by a certain L.G (plus someone called J.L); Bron
https://www.mdpi.com/si/microorganisms/94X32914N7 ..
..“Canadian-born researcher Leona Gilbert at the University of Jyväskylä in Finland
has not only been fired.
Her team has been stripped of its research grants and the university has informed the entire research world about the cheating, something that the
Swedish Yle; Bron
https://svenska.yle.fi/a/7-1502452 was the first to report on.
- I think justice has been done now, says Mats Reimer to SVT Nyheter Väst.
It all started more than three years ago when Leona Gilbert, associate professor of cell and molecular biology, was awarded a fine entrepreneur prize in Finland for her commercial Lyme disease tests. Her own group’s research was the basis for the test, which according to Mats Reimer has not been scientifically evaluated. […]
The university’s investigation team concluded that Leona Gilbert did not even know where the test blood came from,
which made the investigation highly uncertain.
In addition,
she allegedly mixed up different categories of antibodies,
which is considered a serious error.”..
Research misconduct (
fraude) en ontslagen:
Rapport: University of Jyväskylä Finland -
Rector's decision in
2020 en
Yle (Yleisradio Oy of Rundradion Ab, afgekort als Yle, is een Finse publieke omroep) in
2020; Bron
viewtopic.php?f=5&p=30214#p30206 en
Yle (Yleisradio Oy of Rundradion Ab, afgekort als Yle, is een Finse publieke omroep) in
2022; Bron
viewtopic.php?f=5&t=2595&start=460#p30416 en Bron
viewtopic.php?f=5&t=2595&start=130#p29165 en Bron
viewtopic.php?f=5&t=2595&start=130#p2915MDPI -
Special Issue Information van de gast auteurs L.G en J.L; Bron
https://www.mdpi.com/si/microorganisms/94X32914N7 ..Dear Colleagues,
Recently, it was reported that the estimated rate of global Borrelia burgdorferi seropositivity is at 1.2 billion people, and that tick-borne diseases are on the rise. In some countries, tick-borne diseases are not recognized as major health issues, and cases are not officially reported. In addition, in a field of polarized conversation with respect to Post-Treatment Lyme Disease Syndrome (PTLDS), Debilitating Symptom Complexes Attributed To Ticks (DSCATT), or Chronic Lyme (CL), research-based evidence should be allowed to take a place in the narrative. To circumvent the rise in tick-borne disease cases, it is imperative that emerging research in tick-borne pathogens and diseases becomes a focus for many stakeholders and receives the attention it deserves. This Special Issue, entitled “Emerging Research on Tick-Borne Pathogens and Diseases”, seeks the submission of original research papers and comprehensive reviews to create a more inclusive account. The aim of this Special Issue is to provide cutting-edge research that will improve awareness of tick-borne diseases, with the hope that basic research in this area will allow actionable clinical studies to improve awareness and patient outcomes..
..Now
Tezted sells also
tests for
molds and COVID-19..
..He
previously advertised for Tezted product Tickplex e.g.:
O’Loughlin S; Avramovic G; Lambert JS (2019) 'The use of TickPlex Plus in diagnosing Lyme Disease: A comparison to the standard testing methods'. In Irish Journal of Medical Science doi: 10.1007/s11845-019-02130-4; Bron
https://link.springer.com/article/10.10 ... 19-02130-4It was an abstract for the Summer Student Research Awards 2019 at the UCD School of Medicine.
In short, L.G and J.L are the perfect team to run an MDPI special issue.
Reimer told me this: “
It’s sad to see MDPI provide a platform for the pseudo-scientific side in the Lyme wars.“..
Het reeds in
2019 aanprijzen van de
niet-gevalideerde TickPlex test..
Irish Journal of Medical Science (1971 -)
Volume 188, supplement issue 11, December 2019; Bron
https://link.springer.com/journal/11845 ... supplementPublicatie 22 november 2019Study -
'The use of TickPlex Plus in diagnosing Lyme Disease: A comparison to the standard testing methods' by O’Loughlin S1, Avramovic G2, Lambert JS1, 2
1 UCD School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
2 Department of Infectious Disease, Mater Misericordiae University Hospital, University College Dublin, Eccles St, Dublin 7, Ireland.
..Standard testing (ST) for Lyme disease (LD) targets the spirochete form of Borrelia burgdorferi sensu lato. This study aims to compare ST to a new testing platform, *the Tickplex plus (TPP), which tests for spirochetes, round bodies and co-infections. This study will assess if this broader scope of testing improves the diagnosis of persistent LD.
For this cross-sectional study a chart review was performed of 216 charts, with 28 participants deemed eligible. Results from the TTP, ST, self-reported symptom scores and blood tests were extracted. Descriptive statistical analysis, Cohen’s kappa and paired t-tests were used to compare results.
There was a 39.29% agreement between TPP and ST (Cohen’s k: 0.1119). No participants received positive results on ST and negative results on TPP. 59% tested positively on TPP but not ST. 22% tested positively on both TPP and ST. 19% received negative results from both tests. All groups improved with treatment but this was not statiscially significant (p=0.765, p=0.251 p= 0.640). 90% of all participants tested positively for co-infections. 60% of participants with negative results for LD, tested positively for co-infections. 100% of those who tested positively for Borrelia, responded to round bodies, while 75% responded to spirochetes.
As round bodies are associated with persistent infection 1 and co-infections are common in Ireland 2 , their prevalence is unsurprising but unaccounted for by ST. The TPP demonstrates the importance of their inclusion in a comprehensive assay for the diagnosis and management of persistent LD. Further research with a larger sample size is warranted.
References:
1. Garg, K., et al., Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases. Sci Rep, 2018. 8(1): p. 15932.
2. Zintl, A., et al., Ticks and Tick-borne diseases in Ireland. Ir Vet J, 2017. 70: p. 4.
Presenting Author: Sarah O'Loughlin
Supervisor: Prof John Lambert
Co-Supervisor: Ms Gordana Avramovic..
Tezted (Finland) is
fabrikant! en ArminLabs (Duitsland) is
verkoper! van de
kostbare (Basic:
£120 is €140) en
niet-gevalideerde TickPlex Basic test/
IVD (
'in-huis ontwikkelde test')/
RUO Research Use Only
test; en de
kostbare (Plus:
£585 is €686) en
niet-gevalideerde TickPlex Plus test/
IVD (
'in-huis ontwikkelde test')/
RUO Research Use Only
test; en de
kostbare (
£232 is €270) en
niet-gevalideerde ToxiPlex test/
IVD ('
in-huis ontwikkelde test')/
RUO Research Use Only
test.