Kidney disease induced by Lyme disease is quite common in dogs, but it’s not very well-documented in humans. Nevertheless, there’s evidence that chronic Lyme disease can lead to kidney lesions and a type of kidney condition called glomerular disease in some patients.
The glomeruli are the small filtering units within the tissue of the kidney where blood is cleaned of toxic substances. Glomerular disease disrupts the function of the glomeruli, causing the kidney to retain harmful toxins and release proteins and red blood cells into the urine.
Patients with glomerular disease develop a build-up of immunoglobulin A (IgA) deposits in their kidneys – a condition known as Berger’s disease. IgA is an antibody that plays a crucial role in maintaining a healthy immune system. However, excessive IgA deposits can lead to a severe inflammation that damages kidney tissues, especially the glomeruli.
If you’re asking the question ‘Can Lyme disease cause kidney failure?’, unfortunately, the answer is yes. Glomerular disease caused by infection can result in kidney failure. The condition can be fatal if not managed properly. Fortunately, patients have a good chance of making a full recovery when treated with a combination of antibiotics and steroids.
https://www.bca-clinic.com/can-lyme-dis ... y-failure/