Is het een verstandig genomen besluit van Stichting Tekenbeetziekten? Er wordt voorafgaand aan de plaatsneming in de Wetenschappelijke adviescommissie geen 'screening' gedaan en wordt de onderzoekster blind op haar bruine/blauwe ogen geloofd?
Opmerkelijk.. Tezted (Finland) en fabrikant(!) van de
niet-gevalideerde TickPlex test/
IVD ('
in-huis ontwikkelde test')/
RUO Research Use Only test en de
niet-gevalideerde ToxiPlex test/
IVD ('
in-huis ontwikkelde test')/
RUO Research Use Only test zit inmiddels in de Wetenschappelijke adviescommissie van Stichting Tekenbeetziekten?; Bron
https://www.tekenbeetziekten.nl/over-ons/organisatie/ en Bron
viewtopic.php?f=5&t=2595&start=80#p28887..
Wetenschappelijke adviescommissieLeona Gilbert..
..In het kader van onderzoek was dr. Leona Gilbert (CEO for Te?ted Oy and Docent in Cell and Molecular Biology) afgevaardigd door Stichting Tekenbeetziekten. Zij was aanwezig bij zowel het patiëntensymposium als het hoofdcongres..
In een kritisch artikel van de wetenschapsjournalist Schneider van
14 februari 2023 - Chronic Lymerics (Tezted Finland); Bron
https://forbetterscience.com/2023/02/14 ... xcellence/ is opmerkelijke informatie genoemd dat goed is te
verifiëren.
..
MDPI has announced a special issue where you already know what horrors to expect. The journal Microorganisms has an open call for papers for a Special Issue titled “Emerging Research on Tick-Borne Pathogens and Diseases” edited by a certain L.G (plus someone called J.L); Bron
https://www.mdpi.com/si/microorganisms/94X32914N7 ..
..“Canadian-born researcher Leona Gilbert at the University of Jyväskylä in Finland has not only been fired.
Her team has been stripped of its research grants and the university has informed the entire research world about the cheating, something that the Swedish Yle; Bron
https://svenska.yle.fi/a/7-1502452 was the first to report on.
- I think justice has been done now, says Mats Reimer to SVT Nyheter Väst.
It all started more than three years ago when Leona Gilbert, associate professor of cell and molecular biology, was awarded a fine entrepreneur prize in Finland for her commercial Lyme disease tests. Her own group’s research was the basis for the test, which according to Mats Reimer has not been scientifically evaluated. […]
The university’s investigation team concluded that Leona Gilbert did not even know where the test blood came from,
which made the investigation highly uncertain.
In addition,
she allegedly mixed up different categories of antibodies,
which is considered a serious error.”..
MDPI -
Special Issue Information van de gast auteurs L.G en J.L; Bron
https://www.mdpi.com/si/microorganisms/94X32914N7 ..Dear Colleagues,
Recently, it was reported that the estimated rate of global Borrelia burgdorferi seropositivity is at 1.2 billion people, and that tick-borne diseases are on the rise. In some countries, tick-borne diseases are not recognized as major health issues, and cases are not officially reported. In addition, in a field of polarized conversation with respect to Post-Treatment Lyme Disease Syndrome (PTLDS), Debilitating Symptom Complexes Attributed To Ticks (DSCATT), or Chronic Lyme (CL), research-based evidence should be allowed to take a place in the narrative. To circumvent the rise in tick-borne disease cases, it is imperative that emerging research in tick-borne pathogens and diseases becomes a focus for many stakeholders and receives the attention it deserves. This Special Issue, entitled “Emerging Research on Tick-Borne Pathogens and Diseases”, seeks the submission of original research papers and comprehensive reviews to create a more inclusive account. The aim of this Special Issue is to provide cutting-edge research that will improve awareness of tick-borne diseases, with the hope that basic research in this area will allow actionable clinical studies to improve awareness and patient outcomes..
..Now
Tezted sells also
tests for
molds and COVID-19..
..He
previously advertised for Tezted product Tickplex e.g.:
O’Loughlin S; Avramovic G; Lambert JS (2019) 'The use of TickPlex Plus in diagnosing Lyme Disease: A comparison to the standard testing methods'. In Irish Journal of Medical Science doi: 10.1007/s11845-019-02130-4; Bron
https://link.springer.com/article/10.10 ... 19-02130-4It was an abstract for the Summer Student Research Awards 2019 at the UCD School of Medicine.
In short, L.G and J.L are the perfect team to run an MDPI special issue.
Reimer told me this: “It’s sad to see MDPI provide a platform for the pseudo-scientific side in the Lyme wars.“..
Het in
2019 aanprijzen van de
niet-gevalideerde '
TickPlex test'..
Irish Journal of Medical Science (1971 -)
Volume 188, supplement issue 11, December 2019; Bron
https://link.springer.com/journal/11845 ... supplementPublicatie 22 november 2019Study -
'The use of TickPlex Plus in diagnosing Lyme Disease: A comparison to the standard testing methods' by O’Loughlin S1, Avramovic G2, Lambert JS1, 2
1 UCD School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
2 Department of Infectious Disease, Mater Misericordiae University Hospital, University College Dublin, Eccles St, Dublin 7, Ireland.
Standard testing (ST) for Lyme disease (LD) targets the spirochete form of Borrelia burgdorferi sensu lato. This study aims to compare ST to a new testing platform, ***the Tickplex plus (TPP), which tests for spirochetes, round bodies and co-infections. This study will assess if this broader scope of testing improves the diagnosis of persistent LD.
For this cross-sectional study a chart review was performed of 216 charts, with 28 participants deemed eligible. Results from the TTP, ST, self-reported symptom scores and blood tests were extracted. Descriptive statistical analysis, Cohen’s kappa and paired t-tests were used to compare results.
There was a 39.29% agreement between TPP and ST (Cohen’s k: 0.1119). No participants received positive results on ST and negative results on TPP. 59% tested positively on TPP but not ST. 22% tested positively on both TPP and ST. 19% received negative results from both tests. All groups improved with treatment but this was not statiscially significant (p=0.765, p=0.251 p= 0.640). 90% of all participants tested positively for co-infections. 60% of participants with negative results for LD, tested positively for co-infections. 100% of those who tested positively for Borrelia, responded to round bodies, while 75% responded to spirochetes.
As round bodies are associated with persistent infection 1 and co-infections are common in Ireland 2 , their prevalence is unsurprising but unaccounted for by ST. The TPP demonstrates the importance of their inclusion in a comprehensive assay for the diagnosis and management of persistent LD. Further research with a larger sample size is warranted.
References:
1. Garg, K., et al., Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases. Sci Rep, 2018. 8(1): p. 15932.
2. Zintl, A., et al., Ticks and Tick-borne diseases in Ireland. Ir Vet J, 2017. 70: p. 4.
Presenting Author: Sarah O'Loughlin
Supervisor: Prof John Lambert
Co-Supervisor: Ms Gordana Avramovic
Daar waar ik bij het eerder noemen van de informatie en
verifieerbare feiten al enigszins van de stoel was gevallen worden de
feiten opnieuw bevestigd door de wetenschapsjournalist Schneider. En bij mij vallen er steeds meer eurootje/kwartjes op zijn plaats..
'Lyme-helden'?
Met de kennis van nu is er meer en meer duidelijk aan het worden en is de
conclusie: dat de (nieuwe,
geteste en te testen) Lyme/chronische Lyme/Post-lymeziektesyndroom patiënten
jarenlang en tot op heden in het ootje worden genomen (netjes gezegd) waar zij/wij bij staan.
..De publicatie van het artikel van Tezted (Finland) in Nature is op
21 februari 2022 ingetrokken. Dat en de uitspraak van de onderzoekscommissie van de Finse Universiteit worden door de samenwerkend partner Arminlabs (Duitsland) genegeerd?; Bron
https://www.arminlabs.com/nl/tests/tickplex RETRACTED ARTICLE:
'Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases' by Kunal Garg, Leena Meriläinen, Ole Franz, Heidi Pirttinen, Marco Quevedo-Diaz, Stephen Croucher & Leona Gilbert; Bron
https://www.nature.com/articles/s41598-018-34393-9..The Editors have retracted this Article.
The main method utilised in this study is an ELISA assay. An investigation by the University of Jyväskylä, Finland, has concluded that the patient selection and description in this Article, and in an unpublished report validating the methods used, do not justify the results presented. The Editors therefore no longer have confidence in the results and conclusions presented in this Article..
7 september 2020: University of Jyväskylä Finland - Rector's decision on an alleged violation of the responsible conduct of research; Bron
https://www.jyu.fi/en/current/archive/2 ... f-research en Bron
https://lymescience.org/rogues/Leona-Gi ... onduct.pdfDe uitspraak van onderzoekscommissie van de University of Jyväskylä Finland heeft naar verluidt geleid tot het ontslag bij de werkgever de University of Jyväskylä Finland; Bron
https://svenska.yle.fi/a/7-1502452..According to the understanding of the investigation committee, it is unquestionable that opportunistic EBV and CMV infections are observed with a quantitative nucleic acid definition from plasma. Therefore, the use of an antibody test for the same purpose is misleading..
..In its answers, the investigation committee also justified in detail and with references why serology is not suitable for finding opportunistic CMV and EBV infections even though the authors claim so..
..
TARGET OF THE DECISION:
Articles1. A multiplex and multifunctional enzyme linked immunosorbent assay for microbes associated with tick-borne diseases1 (Published on line in 2017; no more available publicly)
2. Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases2; Bron
https://www.nature.com/articles/s41598-018-34393-9
Er is kennelijk ook een
jarenlange samenwerking van Tezted (Finland) met Lyme Resource Centre (LRC) Dublin gaande. Conferentie
14 september 2019 Dublin - 'Tick-borne Disease Diagnostics: The Good the Bad and the Ugly - Dr. Leona Gilbert'; Bron
https://www.youtube.com/watch?v=YNqk3HNHUTc De
Schotse Petitie is afgerond en gesloten op
17 november 2021 en de ingebrachte gronden (de
experimentele en niet-gevalideerde 'Phelix Phage Borrelia test' en de
niet-gevalideerde '
Tickplex test') door Dr J.L en collega Dr J.C (Petitioner en trustee van Lyme Resource Centre) zijn door de Schotse Citizen Participation and Public Petitions Committee en door de Schotse Minister VWS terecht afgewezen; Bron
viewtopic.php?f=5&t=2322&start=980#p29056Petitioner submission of
08 November 2021; Bron
https://www.parliament.scot/chamber-and ... ember-2021..On research, although there is some limited research on testing, it does not include treatment research or our request to implement existing tests. Two tests look potentially useful:
- TickPlex Plus tests for multiple tick-borne infections but we have been told validation of such a test would be difficult because, for most of the infections, there is no existing test to compare it to. We will never make headway unless we start somewhere – though the ideal would be a test which did not rely on antibodies.
- The Phelix Borrelia Phage Test increases the detection of Lyme disease and can distinguish early and late disease. Although it still requires independent validation, we question why the Scottish reference laboratory could not undertake such validation to more quickly bring a promising test to patients..
6 december 2020 - PE1662/SS Petitioner submission of 6 December 2020; Bron
https://www.parliament.scot/S5_PublicPe ... 662_SS.pdf..As stated in previous submissions, only 5 of the 300 known species of Borrelia are currently tested for in Scotland.
Borrelia miyamotoi is known to exist in Scotland
and scientists believe it is responsible for a significant proportion of illness *5.
SLDTRL’s test for Borrelia miyamotoi is not ISO accredited or routinely used, leaving many patients undiagnosed. This may also be the case for other recently discovered species. There is also strong evidence that many Lyme disease patients are also infected with tick-borne co-infections, but SLDTRL has no ISO accredited tests any co-infections..
31 oktober 2020 - PE1662/QQ Professor John S Lambert submission of 31 October 2020; Bron
https://www.parliament.scot/S5_PublicPe ... 662_QQ.pdf15 februari 2020 - PE1662/DD Dr John S Lambert submission of 15 February 2020; Bron
http://www.parliament.scot/S5_PublicPet ... 662_DD.pdf..I support the above petition and wish to highlight the lack of reliable tests and treatment issues that patients face as a result of lack of acknowledgement of their illnesses..
..I am running a conference on tick-borne infections for international researchers on 27th-28th March 2020 in Dublin and invite interested MSPs to attend (complementary registration) to hear from international experts..
6 oktober 2020 - PE1662/OO Petitioner submission of 6 October 2020; Bron
http://www.parliament.scot/S5_PublicPet ... 662_OO.pdf..The Phelix Phage Borrelia test is a new test, developed in conjunction with Leicester University, which is designed to test for bacterial presence and is not dependent 2on host antibody production5. We would like to see this test assessed for routine use in Lyme disease testing in Scotland..
De jarenlange
samenwerking van Tezted en ArminLabs (Duitsland); Bron
viewtopic.php?f=5&t=2595&start=70#p28865 en Bron
viewtopic.php?f=5&t=2595&start=80#p28887 Met de
EliSpot/iSpot Lyme test (na validatie
onbetrouwbaar gebleken) en de
niet-gevalideerde ***Tickplex test kan
géén diagnose worden gesteld en kan
géén behandeling worden gemonitord.
AONM - AONM Interview with Dr Gilbert and Dr Schwarzbach: SARS-Cov-2 Testing - SARSPLEX
11 mei 2020; Bron
https://www.youtube.com/watch?v=4Vnmu_r560k..Dr. Leona Gilbert introduces SARSPLEX, the first Multiplex ELISA to Incorporate Three Immunoglobulins. Clinical implications are further discussed with Dr. Armin Schwarzbach..
De
Sarsplex test is een
niet-gevalideerde test en een
**IVD 'in-huis ontwikkelde test' RUO Research Use Only test.
..Bron
https://www.tezted.com/sarsplex SARSPLEX
RUO COVID - 19 ANTIBODY TEST NOW AVAILABLE..
..The test is an enzyme-linked immunosorbent assay (ELISA)
for research use only..
Kunal Garg (Tezted):
'Apr 21, 2020 We have started shipping #SARSPLEX to our clinical lab partners in Europe. We are highly motivated and are taking actions to meet the ongoing testing demand #COVID19FI #StaySafe #StayHome #AntibodyTest' Bron
https://twitter.com/kunalgargplexLab partner ArminLabs (Duitsland); Bron
https://www.tezted.com/partners en SARS-COV2-ELISA IgG & IgA (Sarsplex test); Bron
https://arminlabs.com/nl/covid19/cov2-elisa-igg-igaDe
niet-gevalideerde ToxiPlex test; Bron
viewtopic.php?f=5&t=2595&start=130#p29159Door ArminLabs (Duitsland) (
verkoper van de testen
TickPlex test,
SarsPlex test,
ToxiPlex test) wordt als samenwerkende partner van Tezted (Finland) (
fabrikant van de testen) als 'bewijs' naar de ingetrokken publicatie verwezen?; Bron
viewtopic.php?f=5&t=2595&start=90#p28904 en Bron
https://www.arminlabs.com/nl/tests/tickplex 26 september 2022: Tezted (Finland): 'Dr. Armin Schwarzbach, M.D. from ArminLabs presented
#tickplex at the 23rd International Lyme and Associated Diseases Society (ILADS) conference in Orlando, Florida!'; Bron
viewtopic.php?f=5&t=2595&start=80#p28894..'Tickplex is Tezted's innovative diagnostic tool that can test for multiple tick-borne disease infections at the same time'..
..'Research outcome 2 Tickplex Basic 3/4 CDC negative are positive for Borrelia persistent forms'..
..'Research outcome 3 Tickplex Basic 95/100 PTLDS patients are positive for Borrelia persistent forms'..
..'85/100 Lyme Disease and multiple microbes associated with tick-borne disease'..
