Morgellon & Borrelia

[Lola Lyme]

Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients
Marianne J Middelveen, Cheryl Bandoski, Jennie Burke, Eva Sapi, Katherine R Filush, Yean Wang, Agustin Franco, Peter J Mayne and Raphael B Stricker
12 February 2015 BMC Dermatology 2015, 15:1 | doi:10.1186/s12895-015-0023-0

Morgellons disease (MD) is a complex skin disorder characterized by ulcerating lesions that have protruding or embedded filaments. Many clinicians refer to this condition as delusional parasitosis or delusional infestation and consider the filaments to be introduced textile fibers. In contrast, recent studies indicate that MD is a true somatic illness associated with tickborne infection, that the filaments are keratin and collagen in composition and that they result from proliferation and activation of keratinocytes and fibroblasts in the skin. Previously, spirochetes have been detected in the dermatological specimens from four MD patients, thus providing evidence of an infectious process.

Methods & Results
Based on culture, histology, immunohistochemistry, electron microscopy and molecular testing, we present corroborating evidence of spirochetal infection in a larger group of 25 MD patients. Irrespective of Lyme serological reactivity, all patients in our study group demonstrated histological evidence of epithelial spirochetal infection. Strength of evidence based on other testing varied among patients. Spirochetes identified as Borrelia strains by polymerase chain reaction (PCR) and/or in-situ DNA hybridization were detected in 24/25 of our study patients. Skin cultures containing Borrelia spirochetes were obtained from four patients, thus demonstrating that the organisms present in dermatological specimens were viable. Spirochetes identified by PCR as Borrelia burgdorferi were cultured from blood in seven patients and from vaginal secretions in three patients, demonstrating systemic infection. Based on these observations, a clinical classification system for MD is proposed.

Conclusions
Our study using multiple detection methods confirms that MD is a true somatic illness associated with Borrelia spirochetes that cause Lyme disease. Further studies are needed to determine the optimal treatment for this spirochete-associated dermopathy.

Lees meer Bron: BMCDermatolgy

[tulpje]

Vanaf 1.01.02:

https://www.youtube.com/watch?v=47ByuAvmSC8

[Lola Lyme]

Morgellons disease: the search for a perpetrator
January 18, 2016

Morgellons disease is a poorly understood skin condition associated with Lyme disease. Patients suffering from the disease often have spontaneously-appearing, slowly-healing skin ulcers and may have crawling or stinging sensations in their skin. They may have one or more typical Lyme disease symptoms such as joint pains, muscle aches, “brain fog” and fatigue. People with this affliction produce microscopic filaments or fibers that project from skin lesions or can be seen under the skin using a handheld microscope. The fibers are often oddly-colored, mostly black, white, red or blue.

Most doctors thought the skin ulcers in Morgellons disease were caused by self-mutilation and that the filaments were textile fibers implanted by patients. Our research has shown that the bizarre filaments seen in skin are not textile fibers, worms, insects or living organisms. Instead, they are composed of collagen and keratin, normal components of skin, hair and nails that are growing in an unusual manner. The blue color seen in the fibers is a pigment called melanin. Melanin is responsible for color in normal human skin and hair.


... Lastly, using sophisticated molecular techniques, we looked for DNA – the molecule providing genetic codes for most living organisms – and searched for sections of code found in Borrelia, but not other organisms. DNA sequencing – the process of determining the exact genetic code – can detect Borrelia DNA, providing the highest level of evidence for spirochete infection.

We found our “perpetrator”. We found evidence of Borrelia infection in 25/25 subjects and DNA evidence in 24/25. Furthermore, we grew living Borrelia spirochetes from skin, blood and vaginal secretions taken from some subjects. We concluded that Morgellons disease is not an illness caused by delusional beliefs but is in reality a skin manifestation of Lyme disease caused by Borrelia spirochetes. Finding the perpetrator will help thousands of suffering people who will benefit from treatment of the underlying infection.

Lees meer Bron: AtlasOfScience

[Roxy]

@LolaLyme,
Dank je wel voor de erg interessante artikelen over Morgellons Disease.

Ontwikkelaar en ervaringsdeskundige van het NB Protocol -wetenschapper en Lyme patiënt- http://www.lyme-morgellons.com/nb-protocol.html geeft op zijn/haar site ook informatie over Morgellons Disease (MD) http://www.lyme-morgellons.com/morgellons.html

[Sproetje]

Hoi Lola,

Even uit je link:

Most doctors thought the skin ulcers in Morgellons disease were caused by self-mutilation and that the filaments were textile fibers implanted by patients.

Ja, dat kan ik me nog herinneren dat er zoiets werd gedacht.
Er was ook heel veel vreemde informatie online hierover.

Our research has shown that the bizarre filaments seen in skin are not textile fibers, worms, insects or living organisms. Instead, they are composed of collagen and keratin, normal components of skin, hair and nails that are growing in an unusual manner. The blue color seen in the fibers is a pigment called melanin. Melanin is responsible for color in normal human skin and hair.

Trouwens, ik zie een verband met het collageen probleem bij lymepatiënten

Borrelia burgdorferi beschadigd elastische vezels en collageen:
viewtopic.php?f=6&t=778

We concluded that Morgellons disease is not an illness caused by delusional beliefs but is in reality a skin manifestation of Lyme disease caused by Borrelia spirochetes.

Eindelijk een beter onderzoek.
Tot nu toe nog weinig goede onderzoeken hier naar gedaan.